Our mission is to ensure the generation of accurate and precise findings.
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TheraOnco aims to use a cancer cell specific metabolism, the Pentose Phosphate Pathway,
to specifically target cancer cells.
We offer to join co-development efforts, through MTA, to characterize this improvement program : in vitro, in vivo POC, before entering regulatory development.
Cancer cells have a specific metabolism to allow fast proliferation. It requires energy and metabolites.
Thus sugar is deeply involve in this modified metabolism, and pentoses have a specific role in there.
Thus pentose is specifically metabolized in cancer cells and can be “presented” on the outer surface of the cell membrane.
Our pentoses are modified, being attached by a click-chemistry hook, that is accessible once metabolized.
Counter-hook can be attached to any chemical (cytotoxic, RadioLigand, fluorophore) or Lipid Nano Particle (LNP), being considered as a payload.
million new cancers per year
million deceased patients per year
times less concentrated cytotoxic
million USD /year lost market value at IP expiration (for each cytotoxic)
Based on cancer cell
metabolism
Highly adaptable solutions
to your specific product
Quickly adaptable to a large number
of oncology indications
Extensive know-how in biochemistry,
cell biology & click-chemistry
